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2126853-17-4

2126853-17-4 structure
2126853-17-4 structure
  • Name: IDO1-IN-15
  • Chemical Name: IDO1-IN-15
  • CAS Number: 2126853-17-4
  • Molecular Formula: C13H14BrFN6O3
  • Molecular Weight: 401.19
  • Create Date: 2022-05-14 10:08:11
  • Modify Date: 2024-04-06 20:48:40
  • IDO1-IN-15 is a potent IDO1 inhibitor (IC50=127 nM). IDO1-IN-15 has comparable potency against IDO1 enzyme in vitro with Epacadostat[1].
Name IDO1-IN-15
Description IDO1-IN-15 is a potent IDO1 inhibitor (IC50=127 nM). IDO1-IN-15 has comparable potency against IDO1 enzyme in vitro with Epacadostat[1].
Related Catalog
Target

IDO1:127 nM (IC50)

In Vitro Cas9-IN-2 is a potent Cas9 inhibitor (IC50=246 μM), Cas9-IN-2 acts by binding to apo-Cas9 to prevent Cas9:gRNA complex formation, which can potentially be applied to modulate and control Cas9 activity in various applications[1].
References

[1]. Wu Y, et al. Discovery of novel IDO1 inhibitors targeting the protein's apo form through scaffold hopping from holo-IDO1 inhibitor. Bioorg Med Chem Lett. 2021;52:128373.

Molecular Formula C13H14BrFN6O3
Molecular Weight 401.19

Chemsrc provides CAS#:2126853-17-4 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 2126853-17-4 | Chemsrc address: https://www.chemsrc.com/en/baike/1705413.html

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