CXCR4 antagonist 5
Modify Date: 2024-01-21 20:07:59
CXCR4 antagonist 5 structure
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Common Name | CXCR4 antagonist 5 | ||
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| CAS Number | 2304749-86-6 | Molecular Weight | 366.50 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H30N6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CXCR4 antagonist 5CXCR4 antagonist 5 (compound 23) is a highly potent CXCR4 antagonist with an IC50 value of 8.8 nM. CXCR4 antagonist 5 can inhibit CXCL12-induced cytosolic calcium increase (IC50 = 0.02 nM) and inhibits CXCR4/CXLC12-mediated chemotaxis. CXCR4 antagonist 5 has good physicochemical properties and in vitro safety profiles, inhibiting CYP isozymes and hERG marginally or moderately[1]. |
| Name | CXCR4 antagonist 5 |
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| Description | CXCR4 antagonist 5 (compound 23) is a highly potent CXCR4 antagonist with an IC50 value of 8.8 nM. CXCR4 antagonist 5 can inhibit CXCL12-induced cytosolic calcium increase (IC50 = 0.02 nM) and inhibits CXCR4/CXLC12-mediated chemotaxis. CXCR4 antagonist 5 has good physicochemical properties and in vitro safety profiles, inhibiting CYP isozymes and hERG marginally or moderately[1]. |
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| Related Catalog | |
| Target |
CXCR4:8.8 nM (IC50) |
| References |
| Molecular Formula | C21H30N6 |
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| Molecular Weight | 366.50 |