Protein kinase affinity probe 1
Modify Date: 2024-01-01 18:31:02
Protein kinase affinity probe 1 structure
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Common Name | Protein kinase affinity probe 1 | ||
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| CAS Number | 2098621-90-8 | Molecular Weight | 531.09 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H39ClN8O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Protein kinase affinity probe 1Protein kinase affinity probe 1 is a novel protein kinase affinity probe for the functional identification of protein kinases (PKs). Protein kinase affinity probe 1 is a modified Purvalanol B (HY-18299) probe with 50% beads loading (Compound S3)[1]. |
| Name | Protein kinase affinity probe 1 |
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| Description | Protein kinase affinity probe 1 is a novel protein kinase affinity probe for the functional identification of protein kinases (PKs). Protein kinase affinity probe 1 is a modified Purvalanol B (HY-18299) probe with 50% beads loading (Compound S3)[1]. |
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| Related Catalog | |
| In Vitro | “S” indicates that the PKI (Purvalanol B) is sepharose-bound[1]. In a series of pull-down experiments from the lysates of HeLa cells, the effects of 0.1, 0.5, 1, 2, 5, 10, 25, and 50% loadings of PK inhibitors is determined. Examine higher bead loadings (75 and 100%) are prevented due to lack of compound solubility and poor reproducibility of the synthesis outcomes. 50% loading is the highest feasible in this study[1]. |
| References |
| Molecular Formula | C26H39ClN8O2 |
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| Molecular Weight | 531.09 |