n-(9-fluorenylmethoxycarbonyl)-l-leucin&

Modify Date: 2024-01-05 20:58:36

n-(9-fluorenylmethoxycarbonyl)-l-leucin& Structure
n-(9-fluorenylmethoxycarbonyl)-l-leucin& structure
Common Name n-(9-fluorenylmethoxycarbonyl)-l-leucin&
CAS Number 200937-57-1 Molecular Weight 354.41
Density N/A Boiling Point N/A
Molecular Formula C21H2315NO4 Melting Point 152-156ºC(lit.)
MSDS Chinese USA Flash Point N/A

 Use of n-(9-fluorenylmethoxycarbonyl)-l-leucin&


Fmoc-leucine-15N is a 15N-labeled and 13C-labled EIDD-1931. EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine ence

 Names

Name N-(9-Fluorenylmethoxycarbonyl)-L-leucine-15N
Synonym More Synonyms

 n-(9-fluorenylmethoxycarbonyl)-l-leucin& Biological Activity

Description Fmoc-leucine-15N is a 15N-labeled and 13C-labled EIDD-1931. EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine ence
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-242.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-242.

 Chemical & Physical Properties

Melting Point 152-156ºC(lit.)
Molecular Formula C21H2315NO4
Molecular Weight 354.41
Exact Mass 354.16000
PSA 75.63000
LogP 4.41530

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3

 Synonyms

L-Leucine-15N,N-Fmoc
Fmoc-Leu-OH-15N
MFCD00209748