4-Chloro-2-(cyclopropylmethoxy)-N-(3-fluoro-4-methoxybenzyl)nicotinamide
Modify Date: 2024-01-21 20:59:06
4-Chloro-2-(cyclopropylmethoxy)-N-(3-fluoro-4-methoxybenzyl)nicotinamide structure
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Common Name | 4-Chloro-2-(cyclopropylmethoxy)-N-(3-fluoro-4-methoxybenzyl)nicotinamide | ||
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| CAS Number | 1629615-99-1 | Molecular Weight | 364.80 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H18ClFN2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 4-Chloro-2-(cyclopropylmethoxy)-N-(3-fluoro-4-methoxybenzyl)nicotinamideALDH2 modulator 1 is a potent and orally active aldehyde dehydrogenase-2 (ALDH2) modulator. ALDH2 modulator 1 reduces blood alcohol levels in mice[1]. |
| Name | ALDH2 modulator 1 |
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| Description | ALDH2 modulator 1 is a potent and orally active aldehyde dehydrogenase-2 (ALDH2) modulator. ALDH2 modulator 1 reduces blood alcohol levels in mice[1]. |
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| Related Catalog | |
| Target |
ALDH2 |
| In Vivo | ALDH2 modulator 1 (compound 161) (10 mg/kg for i.v.; 40, 60 mg/kg for p.o.) 降低经口服 5 g/kg 酒精处理的小鼠的血液酒精水平[1]。 Animal Model: 8-9 weeks, 20-22 g, Male C57BL6 mice (treated with PO 5/kg of EtOH)[1] Dosage: 40, 60 mg/kg for p.o. or 10 mg/kg for i.v. Administration: P.o. or i.v. Result: Reduced blood alcohol levels in mice treated with PO 5 g/kg of EtOH. |
| References |
| Molecular Formula | C18H18ClFN2O3 |
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| Molecular Weight | 364.80 |