N-Acetyl-D-(2,3,3,4,4-2H5)glutamic acid

Modify Date: 2024-02-28 15:48:38

N-Acetyl-D-(2,3,3,4,4-2H5)glutamic acid Structure
N-Acetyl-D-(2,3,3,4,4-2H5)glutamic acid structure
Common Name N-Acetyl-D-(2,3,3,4,4-2H5)glutamic acid
CAS Number 14341-87-8 Molecular Weight 194.20
Density 1.4±0.1 g/cm3 Boiling Point 495.9±35.0 °C at 760 mmHg
Molecular Formula C7H6D5NO5 Melting Point N/A
MSDS N/A Flash Point 253.7±25.9 °C

 Use of N-Acetyl-D-(2,3,3,4,4-2H5)glutamic acid


Ac-D-Glu-OH-d5 is the deuterium labeled Ac-D-Glu-OH.

 Names

Name n-acetyl-d-glutamic-2,3,3,4,4-d5 acid
Synonym More Synonyms

 N-Acetyl-D-(2,3,3,4,4-2H5)glutamic acid Biological Activity

Description Ac-D-Glu-OH-d5 is the deuterium labeled Ac-D-Glu-OH.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 495.9±35.0 °C at 760 mmHg
Molecular Formula C7H6D5NO5
Molecular Weight 194.20
Flash Point 253.7±25.9 °C
Exact Mass 194.095108
PSA 103.70000
LogP -2.24
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.502

 Synonyms

D-Glutamic-2,3,3,4,4-d acid, N-acetyl-
N-Acetyl-D-(2,3,3,4,4-H)glutamic acid