14341-87-8

14341-87-8 structure
14341-87-8 structure
  • Name: N-Acetyl-D-(2,3,3,4,4-2H5)glutamic acid
  • Chemical Name: n-acetyl-d-glutamic-2,3,3,4,4-d5 acid
  • CAS Number: 14341-87-8
  • Molecular Formula: C7H6D5NO5
  • Molecular Weight: 194.20
  • Create Date: 2018-09-18 12:24:46
  • Modify Date: 2024-02-28 15:48:38
  • Ac-D-Glu-OH-d5 is the deuterium labeled Ac-D-Glu-OH.

Name n-acetyl-d-glutamic-2,3,3,4,4-d5 acid
Synonyms D-Glutamic-2,3,3,4,4-d acid, N-acetyl-
N-Acetyl-D-(2,3,3,4,4-H)glutamic acid
Description Ac-D-Glu-OH-d5 is the deuterium labeled Ac-D-Glu-OH.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Density 1.4±0.1 g/cm3
Boiling Point 495.9±35.0 °C at 760 mmHg
Molecular Formula C7H6D5NO5
Molecular Weight 194.20
Flash Point 253.7±25.9 °C
Exact Mass 194.095108
PSA 103.70000
LogP -2.24
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.502