5-Methylcytosine-d4

Modify Date: 2024-04-03 01:43:34

5-Methylcytosine-d4 Structure
5-Methylcytosine-d4 structure
Common Name 5-Methylcytosine-d4
CAS Number 1219795-15-9 Molecular Weight 129.15
Density N/A Boiling Point N/A
Molecular Formula C5H3D4N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-Methylcytosine-d4


5-Methylcytosine-d4 is the deuterium labeled 5-Methylcytosine[1]. 5-Methylcytosine is a well-characterized DNA modification, and is also predominantly in abundant non-coding RNAs in both prokaryotes and eukaryotes. 5-Methylcytosine in mRNA is a new epitranscriptome marker inArabidopsis, and that regulation of this modification is an integral part of gene regulatory networks underlying plant development[2].

 Names

Name 5-Methylcytosine-d4

 5-Methylcytosine-d4 Biological Activity

Description 5-Methylcytosine-d4 is the deuterium labeled 5-Methylcytosine[1]. 5-Methylcytosine is a well-characterized DNA modification, and is also predominantly in abundant non-coding RNAs in both prokaryotes and eukaryotes. 5-Methylcytosine in mRNA is a new epitranscriptome marker inArabidopsis, and that regulation of this modification is an integral part of gene regulatory networks underlying plant development[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Cui X, et al. 5-Methylcytosine RNA Methylation in Arabidopsis Thaliana. Mol Plant. 2017 Nov 6;10(11):1387-1399.  

 Chemical & Physical Properties

Molecular Formula C5H3D4N3O
Molecular Weight 129.15