machilin A

Modify Date: 2025-08-25 17:08:56

machilin A Structure
machilin A structure
Common Name machilin A
CAS Number 110269-50-6 Molecular Weight 326.38600
Density N/A Boiling Point N/A
Molecular Formula C20H22O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of machilin A


Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC50 of 39.9 μM.

 Names

Name machilin A
Synonym More Synonyms

 machilin A Biological Activity

Description Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC50 of 39.9 μM.
Related Catalog
References

[1]. Li G, et al.Melanin biosynthesis inhibitors from the bark of Machilus thunbergii. Biol Pharm Bull. 2003 Jul;26(7):1039-41.  

 Chemical & Physical Properties

Molecular Formula C20H22O4
Molecular Weight 326.38600
Exact Mass 326.15200
PSA 36.92000
LogP 4.20140

 Synonyms

Machilin A
meso-1,4-bis-(3,4-methylenedioxyphenyl)-2,3-dimethylbutane
meso-2,3-Dipiperonyl-butan
meso-machilin A
meso-2,3-dipiperonyl-butane
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