machilin A

Names

[ CAS No. ]:
110269-50-6

[ Name ]:
machilin A

[Synonym ]:
Machilin A
meso-1,4-bis-(3,4-methylenedioxyphenyl)-2,3-dimethylbutane
meso-2,3-Dipiperonyl-butan
meso-machilin A
meso-2,3-dipiperonyl-butane

Biological Activity

[Description]:

Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC50 of 39.9 μM.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Li G, et al.Melanin biosynthesis inhibitors from the bark of Machilus thunbergii. Biol Pharm Bull. 2003 Jul;26(7):1039-41.  

Chemical & Physical Properties

[ Molecular Formula ]:
C20H22O4

[ Molecular Weight ]:
326.38600

[ Exact Mass ]:
326.15200

[ PSA ]:
36.92000

[ LogP ]:
4.20140

Related Compounds

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