110269-50-6

110269-50-6 structure
110269-50-6 structure
  • Name: machilin A
  • Chemical Name: machilin A
  • CAS Number: 110269-50-6
  • Molecular Formula: C20H22O4
  • Molecular Weight: 326.38600
  • Catalog: Research Areas Cancer
  • Create Date: 2018-05-01 14:38:11
  • Modify Date: 2025-08-25 17:08:56
  • Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC50 of 39.9 μM.

Name machilin A
Synonyms Machilin A
meso-1,4-bis-(3,4-methylenedioxyphenyl)-2,3-dimethylbutane
meso-2,3-Dipiperonyl-butan
meso-machilin A
meso-2,3-dipiperonyl-butane
Description Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC50 of 39.9 μM.
Related Catalog
References

[1]. Li G, et al.Melanin biosynthesis inhibitors from the bark of Machilus thunbergii. Biol Pharm Bull. 2003 Jul;26(7):1039-41.  

Molecular Formula C20H22O4
Molecular Weight 326.38600
Exact Mass 326.15200
PSA 36.92000
LogP 4.20140
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