Demecycline

Modify Date: 2024-01-03 10:18:45

Demecycline Structure
Demecycline structure
Common Name Demecycline
CAS Number 987-02-0 Molecular Weight 430.40800
Density 1.69g/cm3 Boiling Point 693.5ºC at 760mmHg
Molecular Formula C21H22N2O8 Melting Point N/A
MSDS N/A Flash Point 373.2ºC

 Use of Demecycline


Demecycline is the C6-demethylated derivative of Tetracycline (HY-A0107) against bacterial infections including pneumonia and other respiratory tract infections[1].

 Names

Name (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
Synonym More Synonyms

 Demecycline Biological Activity

Description Demecycline is the C6-demethylated derivative of Tetracycline (HY-A0107) against bacterial infections including pneumonia and other respiratory tract infections[1].
Related Catalog
References

[1]. Yang W, Kong L, Wang Q, Deng Z, You D. Metabolic engineering of a methyltransferase for production of drug precursors demecycline and demeclocycline in Streptomyces aureofaciens. Synth Syst Biotechnol. 2020;5(3):121-130. Published 2020 Jun 23.

[2]. Results from the Swedish national screening programme 2005.

 Chemical & Physical Properties

Density 1.69g/cm3
Boiling Point 693.5ºC at 760mmHg
Molecular Formula C21H22N2O8
Molecular Weight 430.40800
Flash Point 373.2ºC
Exact Mass 430.13800
PSA 182.61000
LogP 0.76120
Index of Refraction 1.757

 Synonyms

A IX
Demecycline
Demethyltetracycline
Demecyclinum
Demeciclina
Demecycline (USAN/INN)
6-Demethyltetracyclin
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  • DC Chemicals Limited
  • China
  • Product Name: Demecycline
  • Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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Price: ¥900/5 mg

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