5-(N-Methyl-N-isobutyl)-Amiloride structure
|
Common Name | 5-(N-Methyl-N-isobutyl)-Amiloride | ||
|---|---|---|---|---|
| CAS Number | 96861-65-3 | Molecular Weight | 299.76000 | |
| Density | 1.49g/cm3 | Boiling Point | 543.9ºC at 760mmHg | |
| Molecular Formula | C11H18ClN7O | Melting Point | 200-201 °C | |
| MSDS | Chinese USA | Flash Point | 282.8ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
| Name | 3-amino-6-chloro-N-(diaminomethylidene)-5-[methyl(2-methylpropyl)amino]pyrazine-2-carboxamide |
|---|---|
| Synonym | More Synonyms |
| Density | 1.49g/cm3 |
|---|---|
| Boiling Point | 543.9ºC at 760mmHg |
| Melting Point | 200-201 °C |
| Molecular Formula | C11H18ClN7O |
| Molecular Weight | 299.76000 |
| Flash Point | 282.8ºC |
| Exact Mass | 299.12600 |
| PSA | 134.01000 |
| LogP | 2.34230 |
| Index of Refraction | 1.664 |
| InChIKey | RVIUMPLAOXSSGN-UHFFFAOYSA-N |
| SMILES | CC(C)CN(C)c1nc(N)c(C(=O)N=C(N)N)nc1Cl |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | UN 2811 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
|
Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer.
Int. J. Oncol. 46(4) , 1788-800, (2015) We have generated a novel monoclonal antibody (mAb), OCAb9-1, which specifically binds to various types of cancer cell lines, but not to normal cells. According to the results of immunoaffinity chroma... |
|
|
Efficacy and safety of the hypoxia-activated prodrug TH-302 in combination with gemcitabine and nab-paclitaxel in human tumor xenograft models of pancreatic cancer.
Cancer Biol. Ther. 16(3) , 438-49, (2015) Tumors often contain hypoxic regions resistant to chemo- and radiotherapy. TH-302 (T) is an investigational hypoxia-activated prodrug that selectively releases the DNA cross-linker bromo-isophosphoram... |
|
|
Housing temperature-induced stress drives therapeutic resistance in murine tumour models through β2-adrenergic receptor activation.
Nat. Commun. 6 , 6426, (2015) Cancer research relies heavily on murine models for evaluating the anti-tumour efficacy of therapies. Here we show that the sensitivity of several pancreatic tumour models to cytotoxic therapies is si... |
| 5-(N-Methyl-N-isobutyl)amiloride |
| Methylisobutylamiloride |
| MFCD00078567 |
| Lopac-A-5585 |
| 5-Nmnia |
| 3-amino-6-chloro-n-(diaminomethylene)-5-[isobutyl(methyl)amino]pyrazine-2-carboxamide |