Tris(2,4-di-tert-butylphenyl)phosphate

Modify Date: 2024-01-11 19:22:17

Tris(2,4-di-tert-butylphenyl)phosphate structure	Common Name	Tris(2,4-di-tert-butylphenyl)phosphate
	CAS Number	95906-11-9	Molecular Weight	662.92100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₂H₆₃O₄P	Melting Point	99-101 °C(lit.)
	MSDS	N/A	Flash Point	N/A

Use of Tris(2,4-di-tert-butylphenyl)phosphate

Tris(2,4-di-tert-butylphenyl)phosphate is an active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A2 (sPLA2) through molecular docking[1].

Name	tris(2,4-ditert-butylphenyl) phosphate
Synonym	More Synonyms

Description	Tris(2,4-di-tert-butylphenyl)phosphate is an active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A2 (sPLA2) through molecular docking[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase Research Areas >> Inflammation/Immunology
Target	sPLA2[1]
In Vivo	Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP; 50 mg/kg and 70 mg/kg) exhibits significant anti-inflammatory activity in carrageenan induced paw odema model[1]. Tris(2,4-di-tert-butylphenyl)phosphate (50 mg/kg and 70 mg/kg) reduces the raw paw odema volume significantly[1].
References	[1]. Vinuchakkaravarthy T, et al. Active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A(2) through molecular docking. Bioinformation. 2011;7(4):199-206.