LCQ-908

Modify Date: 2024-01-05 22:40:56

LCQ-908 Structure
LCQ-908 structure
Common Name LCQ-908
CAS Number 956136-95-1 Molecular Weight 455.472
Density 1.3±0.1 g/cm3 Boiling Point 611.0±55.0 °C at 760 mmHg
Molecular Formula C25H24F3N3O2 Melting Point N/A
MSDS N/A Flash Point 323.3±31.5 °C

 Use of LCQ-908


Pradigastat (LCQ-908) is a diacylglycerol acyltransferase 1 (DGAT1) inhibitor.

 Names

Name 2-[4-[4-[5-[[6-(trifluoromethyl)pyridin-3-yl]amino]pyridin-2-yl]phenyl]cyclohexyl]acetic acid
Synonym More Synonyms

 LCQ-908 Biological Activity

Description Pradigastat (LCQ-908) is a diacylglycerol acyltransferase 1 (DGAT1) inhibitor.
Related Catalog
In Vivo Pradigastat (LCQ-908) is a potent inhibitor of DGAT1, and has been used for the phase II clinical trials to treat diabetes and obesity[1].
References

[1]. Birch AM, et al. DGAT1 inhibitors as anti-obesity and anti-diabetic agents. Curr Opin Drug Discov Devel. 2010 Jul;13(4):489-96.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 611.0±55.0 °C at 760 mmHg
Molecular Formula C25H24F3N3O2
Molecular Weight 455.472
Flash Point 323.3±31.5 °C
Exact Mass 455.182068
PSA 75.11000
LogP 6.10
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.582
Storage condition 2-8℃

 Synonyms

Pradigastat [INN]
{trans-4-[4-(5-{[6-(Trifluoromethyl)-3-pyridinyl]amino}-2-pyridinyl)phenyl]cyclohexyl}acetic acid
Cyclohexaneacetic acid, 4-[4-[5-[[6-(trifluoromethyl)-3-pyridinyl]amino]-2-pyridinyl]phenyl]-, trans-
LCQ 908
Pradigastat
LCQ 908NXA
UNII-2U23G6VNUZ
LCQ908-NXA
LCQ-908
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Price: $377/10mM*1mLinDMSO

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