PC190723

Modify Date: 2025-08-27 08:36:17

PC190723 Structure
PC190723 structure
Common Name PC190723
CAS Number 951120-33-5 Molecular Weight 355.75
Density N/A Boiling Point N/A
Molecular Formula C14H8ClF2N3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PC190723


PC190723 (Compound 2) is an inhibitor of the bacterial cell division protein FtsZ with an IC50 of 55 ng/ml. FtsZ-IN-3 exhibits anti-staphylococcal activity with MIC values of 1 µg/ml for MSSA and MRSA[1].

 Names

Name 3-[(6-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide
Synonym More Synonyms

 PC190723 Biological Activity

Description PC190723 (Compound 2) is an inhibitor of the bacterial cell division protein FtsZ with an IC50 of 55 ng/ml. FtsZ-IN-3 exhibits anti-staphylococcal activity with MIC values of 1 µg/ml for MSSA and MRSA[1].
Related Catalog
Target

IC50: 55 ng/ml (FtsZ)[1]

References

[1]. Buroni S, et al. The cell division protein FtsZ as a cellular target to hit cystic fibrosis pathogens. Eur J Med Chem. 2020 Mar 15;190:112132.

 Chemical & Physical Properties

Molecular Formula C14H8ClF2N3O2S
Molecular Weight 355.75
Exact Mass 354.99900
PSA 106.34000
LogP 4.00110

 Synonyms

9pc
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