951120-33-5

951120-33-5 structure

Name: PC190723
Chemical Name: 3-[(6-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide
CAS Number: 951120-33-5
Molecular Formula: C₁₄H₈ClF₂N₃O₂S
Molecular Weight: 355.75
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2016-05-09 17:00:18
Modify Date: 2025-08-27 08:36:17
PC190723 (Compound 2) is an inhibitor of the bacterial cell division protein FtsZ with an IC50 of 55 ng/ml. FtsZ-IN-3 exhibits anti-staphylococcal activity with MIC values of 1 µg/ml for MSSA and MRSA[1].

Name	3-[(6-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide
Synonyms	9pc

Description	PC190723 (Compound 2) is an inhibitor of the bacterial cell division protein FtsZ with an IC50 of 55 ng/ml. FtsZ-IN-3 exhibits anti-staphylococcal activity with MIC values of 1 µg/ml for MSSA and MRSA[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 55 ng/ml (FtsZ)[1]
References	[1]. Buroni S, et al. The cell division protein FtsZ as a cellular target to hit cystic fibrosis pathogens. Eur J Med Chem. 2020 Mar 15;190:112132.