1H-Benzotriazole

Modify Date: 2024-01-02 11:57:23

1H-Benzotriazole Structure
1H-Benzotriazole structure
Common Name 1H-Benzotriazole
CAS Number 95-14-7 Molecular Weight 119.12
Density 1.3±0.1 g/cm3 Boiling Point 204 ºC (15 mmHg)
Molecular Formula C6H5N3 Melting Point 97-99 °C(lit.)
MSDS Chinese USA Flash Point 170 ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of 1H-Benzotriazole


1H-Benzo[d][1,2,3]triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name benzotriazole
Synonym More Synonyms

 1H-Benzotriazole Biological Activity

Description 1H-Benzo[d][1,2,3]triazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro 1,2,3-苯并三唑是一种含有三个氮原子的杂环化合物,化学式为C6H5N3。这种芳香族化合物是无色和极性的,可用于各种领域。

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 204 ºC (15 mmHg)
Melting Point 97-99 °C(lit.)
Molecular Formula C6H5N3
Molecular Weight 119.12
Flash Point 170 ºC
Exact Mass 119.048347
PSA 41.57000
LogP 1.34
Vapour density 4.1 (vs air)
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.715
Stability Stable, but may be light sensitive. Incompatible with strong oxidizing agents, heavy metals.
Water Solubility 25 g/l in water (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DM1225000
CHEMICAL NAME :
1H-Benzotriazole
CAS REGISTRY NUMBER :
95-14-7
BEILSTEIN REFERENCE NO. :
0112133
LAST UPDATED :
199710
DATA ITEMS CITED :
21
MOLECULAR FORMULA :
C6-H5-N3
MOLECULAR WEIGHT :
119.14
WISWESSER LINE NOTATION :
T56 BMNNJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
560 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1910 mg/m3/3H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
615 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
238 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
109 mg/kg/26W-I
TOXIC EFFECTS :
Endocrine - other changes Blood - normocytic anemia Blood - leukopenia
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
220 gm/kg/78W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
770 gm/kg/78W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Lungs, Thorax, or Respiration - bronchiogenic carcinoma

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - rat Embryo
DOSE/DURATION :
94 ug/plate
REFERENCE :
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 1,190,1981 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82113 No. of Facilities: 1661 (estimated) No. of Industries: 23 No. of Occupations: 33 No. of Employees: 5550 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82113 No. of Facilities: 17143 (estimated) No. of Industries: 144 No. of Occupations: 107 No. of Employees: 279549 (estimated) No. of Female Employees: 40869 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302 + H332-H319-H412
Precautionary Statements P273-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes F:Flammable
Risk Phrases R11;R20/21/22;R36/37/38;R5
Safety Phrases S26-S36/37-S61-S45-S36/37/39-S28A
RIDADR 2811
WGK Germany 1
RTECS DM1225000
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

BENZOTRIAZOLE PHOTOGRADE
1H-Benzo[d][1,2,3]triazole
Benzotriazol
HETEROCYLIC NITROGEN
cobratec99
1h-benzo
U-6233
1, 2, 3 BENZOTRIAZOLE
T706
1,2,3-1H-Benzotriazole
Seetec BT
1H-benzo[1,2,3]triazole
Cobratec
MFCD00005699
EINECS 202-394-1
1,2,3-BENZOTRIALOLE ( BTA )
1,2,3-BENZOTRIAZOLE,1H-BENZO[D][1,2,3]TRIAZOLE
1,2,3-Benzotriazole(electronicgrade)
1.2.3-Benzotrialole
1,2,3-Benzotriazole
1,2,3-triazaindene
1,2,3,-BENZOTRIAZOLE
Benzotriazole (BTA)
BTA
T56 BMNNJ
1,2,3-Benzotriazole BTA
1,2,3-BENZO TRIAZOLE
RusMin R
1H-BENZOTRIAZOLE FOR SYNTHESIS
1H-1,2,3-Benzotriazole
1H-Benzotriazole
1,2,3-triaza-1H-indene
1,2,3 BENZOTRIAZOLE (BTA)
1,2,3-BENZOTRIAZOL ZUR SYNTHESE
1H-BENZOTRIAZOLE (BTA)
Benzotriazole
BLS 1326
1,2,3-Benzotriazole(BTA)
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