Senkyunolide I

Modify Date: 2025-08-23 16:03:15

Senkyunolide I Structure
Senkyunolide I structure
Common Name Senkyunolide I
CAS Number 94596-28-8 Molecular Weight 224.253
Density 1.3±0.1 g/cm3 Boiling Point 444.8±45.0 °C at 760 mmHg
Molecular Formula C12H16O4 Melting Point N/A
MSDS N/A Flash Point 175.1±22.2 °C

 Use of Senkyunolide I


Senkyunolide I, isolated from Ligusticum chuanxiong Hort, is an anti-migraine compound. Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3[1][2].

 Names

Name Senkyunolide I
Synonym More Synonyms

 Senkyunolide I Biological Activity

Description Senkyunolide I, isolated from Ligusticum chuanxiong Hort, is an anti-migraine compound. Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3[1][2].
Related Catalog
References

[1]. Wang YH, et al. Effect and mechanism of senkyunolide I as an anti-migraine compound from Ligusticum chuanxiong. J Pharm Pharmacol. 2011 Feb;63(2):261-6.

[2]. Hu Y, et al. Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3. Brain Res. 2015 Apr 24;1605:39-48.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 444.8±45.0 °C at 760 mmHg
Molecular Formula C12H16O4
Molecular Weight 224.253
Flash Point 175.1±22.2 °C
Exact Mass 224.104858
PSA 66.76000
LogP 1.04
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.571
Storage condition 2-8℃

 Safety Information

Hazard Codes Xi

 Synonyms

seneciphyllin
1(3H)-Isobenzofuranone, 3-butylidene-4,5,6,7-tetrahydro-6,7-dihydroxy-, (3Z,6S,7S)-
SenkyunolideI
(3Z,6S,7S)-3-Butylidene-6,7-dihydroxy-4,5,6,7-tetrahydro-2-benzofuran-1(3H)-one
UNII:12PJ07292V
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here





Get all suppliers and price by the below link:

Senkyunolide I suppliers

Senkyunolide I price