NIBR-17

Modify Date: 2024-01-03 19:29:20

NIBR-17 Structure
NIBR-17 structure
Common Name NIBR-17
CAS Number 944396-88-7 Molecular Weight 380.40
Density 1.4±0.1 g/cm3 Boiling Point 718.3±70.0 °C at 760 mmHg
Molecular Formula C18H20N8O2 Melting Point N/A
MSDS N/A Flash Point 388.2±35.7 °C

 Use of NIBR-17


NIBR-17 is a pan-class I PI3K inhibitor with suitable pharmacokinetic properties and inhibits tumor growth[1].

 Names

Name [4,5'-Bipyrimidine]-2',6-diamine, N6-(6-methoxy-3-pyridinyl)-2-(4-morpholinyl)
Synonym More Synonyms

 NIBR-17 Biological Activity

Description NIBR-17 is a pan-class I PI3K inhibitor with suitable pharmacokinetic properties and inhibits tumor growth[1].
Related Catalog
References

[1]. Burger MT, et al. Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors. ACS Med Chem Lett. 2010 Oct 13;2(1):34-8.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 718.3±70.0 °C at 760 mmHg
Molecular Formula C18H20N8O2
Molecular Weight 380.40
Flash Point 388.2±35.7 °C
Exact Mass 380.170929
PSA 124.20000
LogP 2.00
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.671
Storage condition -20°C

 Synonyms

5-(6-(6-methoxypyridin-3-ylamino)-2-morpholinopyrimidin-4-yl)pyrimidin-2-amine
N-(6-Methoxy-3-pyridinyl)-2-(4-morpholinyl)-4,5'-bipyrimidine-2',6-diamine
[4,5'-Bipyrimidine]-2',6-diamine, N-(6-methoxy-3-pyridinyl)-2-(4-morpholinyl)-
NIBR-17