Suc-Leu-Tyr-AMC
Suc-Leu-Tyr-AMC structure
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Common Name | Suc-Leu-Tyr-AMC | ||
|---|---|---|---|---|
| CAS Number | 94367-20-1 | Molecular Weight | 551.58800 | |
| Density | 1.324g/cm3 | Boiling Point | 945.5ºC at 760mmHg | |
| Molecular Formula | C29H33N3O8 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 525.6ºC | |
Use of Suc-Leu-Tyr-AMCSuc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the chymotrypsin-like peptidase activity of the 20S proteasome |
| Name | N-succinyl-Leu-Tyr-7-amido-4-methylcoumarin |
|---|---|
| Synonym | More Synonyms |
| Density | 1.324g/cm3 |
|---|---|
| Boiling Point | 945.5ºC at 760mmHg |
| Molecular Formula | C29H33N3O8 |
| Molecular Weight | 551.58800 |
| Flash Point | 525.6ºC |
| Exact Mass | 551.22700 |
| PSA | 175.04000 |
| LogP | 3.72350 |
| Index of Refraction | 1.611 |
| Storage condition | −20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates.
J. Biol. Chem. 259 , 12489, (1984) Homogeneous porcine calpain (Ca2+-dependent cysteine proteinase) was found to hydrolyze a variety of peptides and synthetic substrates. Leu-Trp-Met-Arg-Phe-Ala, eledoisin-related peptide, alpha-neoend... |
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Inhibition of chicken calpain II by proteins of the cystatin superfamily and alpha 2-macroglobulin.
Biochem. J. 248(2) , 589-94, (1987) Inhibition of chicken calpain II by proteins of the cystatin superfamily and alpha 2-macroglobulin was investigated. Human liver cystatins A and B, human cystatin C, chicken cystatin and rat T-kininog... |
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Probing of primed and unprimed sites of calpains: Design, synthesis and evaluation of epoxysuccinyl-peptide derivatives as selective inhibitors.
Eur. J. Med. Chem. 82 , 274-80, (2014) Calpains are intracellular cysteine proteases with important physiological functions. Up- or downregulation of their expression can be responsible for several diseases, therefore specific calpain inhi... |
| CALPAIN SUBSTRATE II,FLUOROGENIC |
| N-SUCCINYL-LEU-TYR 4-METHYLCOUMARYL-7-AMIDE |
| succinyl-leucyl-tyrosyl-4-methyl-7-coumarylamide |
| N-SUCCINYL-LEU-TYR 7-AMIDO-4-METHYLCOUMARIN |
| CALPAIN SUBSTRATE I |
| SUC-LEU-TYR-AMC |
| SUC-LY-AMC |
| SUCCINYL-LEU-TYR-AMC |
| SUC-LEU-TYR-7-AMINO-4-METHYLCOUMARIN |
| MFCD00057900 |
- GL Biochem (Shanghai) Ltd.
- China
- Product Name: Suc-Leu-Tyr-AMC;Suc-LY-AMC
- Price: $Inquiry/1g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Jackie Yang
- Nanjing Peptide Biotech Ltd
- China
- Product Name: Suc-Leu-Tyr-AMC
- Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
- Purity: 98.0%
- Stocking Period: 7 Day
- Contact: jom
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