Phen-DC 3

Modify Date: 2024-01-05 19:04:52

Phen-DC 3 Structure
Phen-DC 3 structure
Common Name Phen-DC 3
CAS Number 942936-75-6 Molecular Weight 550.61
Density N/A Boiling Point N/A
Molecular Formula C34H26N6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Phen-DC 3


Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively.

 Names

Name Phen-DC3

 Phen-DC 3 Biological Activity

Description Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively.
Related Catalog
Target

IC50: 65±6 nM (G4 substrate, FANCJ helicase), 50±10 nM (G4 substrate, DinG helicases)[1].

References

[1]. Bharti SK, et al. Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability. J Biol Chem. 2013 Sep 27; 288(39):28217-29.

 Chemical & Physical Properties

Molecular Formula C34H26N6O2
Molecular Weight 550.61