MK-7288
Modify Date: 2025-08-23 23:09:24
MK-7288 structure
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Common Name | MK-7288 | ||
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| CAS Number | 936626-07-2 | Molecular Weight | 401.499 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 622.5±55.0 °C at 760 mmHg | |
| Molecular Formula | C22H31N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 330.2±31.5 °C | |
Use of MK-7288A novel histamine H3 receptor inverse agonist for the treatment of sleep apnoea syndrome; significantly prolongs MWT sleep latency, and improves car driving simulation standard deviation of lane position in clinical trials. Sleep Disorder Phase 1 Clinical |
| Name | (1r,4r)-2'-Methoxy-N-methyl-7'-oxo-N-[2-(1-piperidinyl)ethyl]-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine]-4-carboxamide |
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| Synonym | More Synonyms |
| Description | A novel histamine H3 receptor inverse agonist for the treatment of sleep apnoea syndrome; significantly prolongs MWT sleep latency, and improves car driving simulation standard deviation of lane position in clinical trials. Sleep Disorder Phase 1 Clinical |
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| References | References 1. Sun H, et al. J Clin Pharmacol. 2013 Dec;53(12):1294-302. View Related Products by Target Histamine Receptor Sleep Disorder |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 622.5±55.0 °C at 760 mmHg |
| Molecular Formula | C22H31N3O4 |
| Molecular Weight | 401.499 |
| Flash Point | 330.2±31.5 °C |
| Exact Mass | 401.231445 |
| LogP | 1.73 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.587 |
| Spiro[cyclohexane-1,5'(7'H)-furo[3,4-b]pyridine]-4-carboxamide, 2'-methoxy-N-methyl-7'-oxo-N-[2-(1-piperidinyl)ethyl]- |
| (1r,4r)-2'-Methoxy-N-methyl-7'-oxo-N-[2-(1-piperidinyl)ethyl]-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine]-4-carboxamide |