HMMNI

Modify Date: 2024-01-03 07:27:27

HMMNI Structure
HMMNI structure
Common Name HMMNI
CAS Number 936-05-0 Molecular Weight 157.127
Density 1.5±0.1 g/cm3 Boiling Point 388.0±22.0 °C at 760 mmHg
Molecular Formula C5H7N3O3 Melting Point 110-112ºC
MSDS USA Flash Point 188.5±22.3 °C

 Use of HMMNI


HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class drug that combats protozoan infections[1][2].

 Names

Name (1-Methyl-5-nitro-1H-imidazol-2-yl)methanol
Synonym More Synonyms

 HMMNI Biological Activity

Description HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class drug that combats protozoan infections[1][2].
Related Catalog
References

[1]. Cronly M, et al. Rapid confirmatory method for the determination of 11 nitroimidazoles in egg using liquid chromatography tandem mass spectrometry. J Chromatogr A. 2009;1216(46):8101‐8109.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 388.0±22.0 °C at 760 mmHg
Melting Point 110-112ºC
Molecular Formula C5H7N3O3
Molecular Weight 157.127
Flash Point 188.5±22.3 °C
Exact Mass 157.048737
PSA 83.87000
LogP -0.49
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.634
Storage condition -20?C Freezer

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NI6801000
CHEMICAL NAME :
Imidazole-2-methanol, 1-methyl-5-nitro-
CAS REGISTRY NUMBER :
936-05-0
BEILSTEIN REFERENCE NO. :
0744944
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C5-H7-N3-O3
MOLECULAR WEIGHT :
157.15
WISWESSER LINE NOTATION :
T5N CNJ A1 B1Q ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Klebsiella pneumoniae
DOSE/DURATION :
10 umol/L/20H
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 66,207,1979

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
RTECS NI6801000
HS Code 2933290090

 Synthetic Route

~82%

HMMNI Structure

HMMNI

CAS#:936-05-0

Literature: Adebayo, Adelaide T. O. M.; Bowman, W. Russell; Salt, W. G. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 2819 - 2828

~57%

HMMNI Structure

HMMNI

CAS#:936-05-0

Literature: ANGIOGENE PHARMACEUTICALS LIMITED; THE GRAY LABORATORY CANCER RESEARCH TRUST Patent: WO2006/32921 A1, 2006 ; Location in patent: Page/Page column 35-36 ;

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HMMNI Structure

HMMNI

CAS#:936-05-0

Literature: Journal of Medicinal Chemistry, , vol. 43, # 11 p. 2258 - 2265

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HMMNI Structure

HMMNI

CAS#:936-05-0

Literature: US4010176 A1, ;

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HMMNI Structure

HMMNI

CAS#:936-05-0

Literature: Journal of Medicinal Chemistry, , vol. 43, # 11 p. 2258 - 2265

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HMMNI Structure

HMMNI

CAS#:936-05-0

Literature: Journal of Medicinal Chemistry, , vol. 43, # 11 p. 2258 - 2265

 Customs

HS Code 2933290090
Summary 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles4

More Articles
Simultaneous determination of nitroimidazole residues in honey samples by high-performance liquid chromatography with ultraviolet detection.

J. AOAC Int. 90(3) , 872-8, (2007)

A rapid and sensitive high-performance liquid chromatography (LC) method was developed for the simultaneous determination of metronidazole (MNZ), dimetridazole (DMZ), ronidazole (RNZ), tinidazole (TNZ...

Confirmation of four nitroimidazoles in porcine liver by liquid chromatography-tandem mass spectrometry.

Anal. Chim. Acta 586(1-2) , 394-8, (2007)

A sensitive and reliable multiresidue method is described for analysis of ronidazole, metronidazole, dimetridazole and the common metabolite of ronidazole and dimetridazole, 2-hydroxymethyl-1-methyl-5...

Pharmacokinetics and anti-trichomonal efficacy of a dimetridazole tablet and water-soluble powder in homing pigeons (Columba livia).

J. Vet. Pharmacol. Ther. 19(1) , 62-7, (1996)

The anti-trichomonal efficacy and pharmacokinetics of dimetridazole were investigated in the homing pigeon (Columba livia). Dimetridazole was formulated for drinking water medication and as a prolonge...

 Synonyms

1-Methyl-2-hydroxymethyl-5-nitroimidazole
imidazole-2-methanol, 1-methyl-5-nitro-
1-Methyl-5-nitro-1H-imidazole-2-methanol
2-hydroxymethyl-1-methyl-5-nitroimidazole
1H-Imidazole-2-methanol, 1-methyl-5-nitro-
(1-Methyl-5-nitro-1H-imidazol-2-yl)methanol
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  • DC Chemicals Limited
  • China
  • Product Name: HMMNI
  • Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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