N-Methyl-2-pyrrolidone-d3

Modify Date: 2023-02-01 10:12:26

N-Methyl-2-pyrrolidone-d3 Structure
N-Methyl-2-pyrrolidone-d3 structure
Common Name N-Methyl-2-pyrrolidone-d3
CAS Number 933-86-8 Molecular Weight 99.13110
Density N/A Boiling Point N/A
Molecular Formula C5H9NO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Methyl-2-pyrrolidone-d3


N-Methyl-2-pyrrolidone-d3 is the deuterium labeled N-Methylpyrrolidone[1]. N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an organic polar solvent. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals[2][3].

 Names

Name 1-(trideuteriomethyl)pyrrolidin-2-one
Synonym More Synonyms

 N-Methyl-2-pyrrolidone-d3 Biological Activity

Description N-Methyl-2-pyrrolidone-d3 is the deuterium labeled N-Methylpyrrolidone[1]. N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an organic polar solvent. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Jing Wang, et al. Nitrate stimulation of N-Methylpyrrolidone biodegradation by Paracoccus pantotrophus: Metabolite mechanism and Genomic characterization. Bioresour Technol. 2019 Dec;294:122185.  

[3]. Claudia Julieta Solís-González, et al. Novel Metabolic Pathway for N-Methylpyrrolidone Degradation in Alicycliphilus sp. Strain BQ1. Appl Environ Microbiol. 2017 Dec 1584(1):e02136-17.  

 Chemical & Physical Properties

Molecular Formula C5H9NO
Molecular Weight 99.13110
Exact Mass 99.06840
PSA 20.31000
LogP 0.17650

 Synonyms

Pharmasolve-d3
N-Methylpyrrolidone-d3
N-Trideuteriomethyl-2-pyrrolidon
M-Pyrol-d3
NMP-d3
1-Methylpyrrolidone-d3
N-Methyl-|A-butyrolactam-d3
Microposit 2001-d3
AgsolEx 1-d3
Pyrol M-d3
N-Methylbutyrolactam-d3