VRX-0466617

Modify Date: 2024-01-08 20:20:58

VRX-0466617 Structure
VRX-0466617 structure
Common Name VRX-0466617
CAS Number 926906-64-1 Molecular Weight 462.36
Density 1.6±0.1 g/cm3 Boiling Point 545.4±60.0 °C at 760 mmHg
Molecular Formula C19H20BrN5O2S Melting Point N/A
MSDS N/A Flash Point 283.6±32.9 °C

 Use of VRX-0466617


VRX0466617, a selective Chk2 inhibitor, inhibits the phosphorylation of Chk2 Ser 19 and Ser33-35. VRX0466617 can be used in the study of cancer[1].

 Names

Name VRX-0466617
Synonym More Synonyms

 VRX-0466617 Biological Activity

Description VRX0466617, a selective Chk2 inhibitor, inhibits the phosphorylation of Chk2 Ser 19 and Ser33-35. VRX0466617 can be used in the study of cancer[1].
Related Catalog
References

[1]. Carlessi L, et al. Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2. Mol Cancer Ther. 2007 Mar;6(3):935-44.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 545.4±60.0 °C at 760 mmHg
Molecular Formula C19H20BrN5O2S
Molecular Weight 462.36
Flash Point 283.6±32.9 °C
Exact Mass 461.052094
LogP 3.06
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.714
Storage condition store at -20℃ for one year(Powder)

 Synonyms

5-({4-[(4-bromophenyl)amino]phenyl}amino)-3-hydroxy-N-(1-hydroxypropan-2-yl)-1,2-thiazole-4-carboximidamide
4-Isothiazolecarboximidamide, 5-[[4-[(4-bromophenyl)amino]phenyl]amino]-2,3-dihydro-N-(2-hydroxy-1-methylethyl)-3-oxo-
5-({4-[(4-Bromophenyl)amino]phenyl}amino)-N-(1-hydroxy-2-propanyl)-3-oxo-2,3-dihydro-1,2-thiazole-4-carboximidamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.