LAS101057
Modify Date: 2025-08-26 10:45:47
LAS101057 structure
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Common Name | LAS101057 | ||
|---|---|---|---|---|
| CAS Number | 925676-48-8 | Molecular Weight | 335.33500 | |
| Density | 1.400±0.06 g/cm3 (20 °C, 760 mmHg) | Boiling Point | 509.2±50.0 °C (760 mmHg) | |
| Molecular Formula | C18H14FN5O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LAS101057LAS101057 is a potent, selective, and orally efficacious A2B receptor antagonist. |
| Name | Cyclopropanecarboxamide, N-[5-(3-fluoro-4-pyridinyl)-6-(3-pyridinyl)-2-pyrazinyl] |
|---|---|
| Synonym | More Synonyms |
| Description | LAS101057 is a potent, selective, and orally efficacious A2B receptor antagonist. |
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| Related Catalog | |
| In Vivo | At 3 mg/kg, LAS101057 is active in preventing methacholine-induced AHR, and at 10 mg/kg it inhibits AHR to methacholine to a level virtually equal to that seen with dexamethasone at 1 mg/kg[1]. |
| References |
| Density | 1.400±0.06 g/cm3 (20 °C, 760 mmHg) |
|---|---|
| Boiling Point | 509.2±50.0 °C (760 mmHg) |
| Molecular Formula | C18H14FN5O |
| Molecular Weight | 335.33500 |
| Exact Mass | 335.11800 |
| PSA | 80.66000 |
| LogP | 3.16120 |
| InChIKey | XUYURJQIMYCWBB-UHFFFAOYSA-N |
| SMILES | O=C(Nc1cnc(-c2ccncc2F)c(-c2cccnc2)n1)C1CC1 |
| las-101057 |
| LAS101057 |