PqsR/LasR-IN-1

Modify Date: 2025-11-30 17:53:10

PqsR/LasR-IN-1 Structure
PqsR/LasR-IN-1 structure
Common Name PqsR/LasR-IN-1
CAS Number 924818-33-7 Molecular Weight 405.87
Density N/A Boiling Point N/A
Molecular Formula C24H20ClNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PqsR/LasR-IN-1


PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of PqsR and LasR systems in P. aeruginosa. PqsR/LasR-IN-1 also inhibits hERG with the IC50 of 6.77 µM[1].

 Names

Name PqsR/LasR-IN-1

 PqsR/LasR-IN-1 Biological Activity

Description PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of PqsR and LasR systems in P. aeruginosa. PqsR/LasR-IN-1 also inhibits hERG with the IC50 of 6.77 µM[1].
Related Catalog
Target

Pseudomonas aeruginosa[1]

References

[1]. Mohammad Anwar Hossain, et al. Design, synthesis, and evaluation of compounds capable of reducing Pseudomonas aeruginosa virulence. Eur J Med Chem. 2020 Jan 1;185:111800.

 Chemical & Physical Properties

Molecular Formula C24H20ClNO3
Molecular Weight 405.87
InChIKey WMGRTKLFMHNQKG-UHFFFAOYSA-N
SMILES Cc1ccc(NC(=O)c2ccc3c(c2)CC(c2ccc(Cl)cc2)OC3=O)cc1C
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