AZD-5597
Modify Date: 2025-08-29 08:25:02
AZD-5597 structure
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Common Name | AZD-5597 | ||
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| CAS Number | 924641-59-8 | Molecular Weight | 437.51 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H28FN7O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AZD-5597AZD5597 is an inhibitor of CDK with an IC50 of 2 nM. AZD5597 has potent anti-proliferative effects against a range of cancer cell lines[1]. |
| Name | [4-[[5-fluoro-4-(2-methyl-3-propan-2-ylimidazol-4-yl)pyrimidin-2-yl]amino]phenyl]-[(3S)-3-(methylamino)pyrrolidin-1-yl]methanone |
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| Synonym | More Synonyms |
| Description | AZD5597 is an inhibitor of CDK with an IC50 of 2 nM. AZD5597 has potent anti-proliferative effects against a range of cancer cell lines[1]. |
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| Related Catalog | |
| Target |
IC50: 2 nM (CDK2), 2 nM (CDK1), 39 nM (LoVo)[1] |
| References |
| Molecular Formula | C23H28FN7O |
|---|---|
| Molecular Weight | 437.51 |
| Exact Mass | 437.23400 |
| PSA | 87.97000 |
| LogP | 3.94780 |
| InChIKey | NTSDIJMNXYJJNG-SFHVURJKSA-N |
| SMILES | CNC1CCN(C(=O)c2ccc(Nc3ncc(F)c(-c4cnc(C)n4C(C)C)n3)cc2)C1 |
| UNII-N7855W19GY |
| AZD-5597 |
| (S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone |