(22R)-14,20,22-Trihydroxy-1-oxoergosta-3,5,24-triene-18,26-dioic acid 18,20:26,22-dilactone

Modify Date: 2025-08-26 11:53:07

(22R)-14,20,22-Trihydroxy-1-oxoergosta-3,5,24-triene-18,26-dioic acid 18,20:26,22-dilactone Structure
(22R)-14,20,22-Trihydroxy-1-oxoergosta-3,5,24-triene-18,26-dioic acid 18,20:26,22-dilactone structure
Common Name (22R)-14,20,22-Trihydroxy-1-oxoergosta-3,5,24-triene-18,26-dioic acid 18,20:26,22-dilactone
CAS Number 91599-21-2 Molecular Weight 295.763
Density 1.2±0.1 g/cm3 Boiling Point 451.6±45.0 °C at 760 mmHg
Molecular Formula C18H14ClNO Melting Point N/A
MSDS N/A Flash Point 226.9±28.7 °C

 Use of (22R)-14,20,22-Trihydroxy-1-oxoergosta-3,5,24-triene-18,26-dioic acid 18,20:26,22-dilactone


Withaphysalin D is a selective antagonist against the N-methyl-D-aspartate receptor (NMDAR) containing GluN2B. Withaphysalin D can be isolated from water lilies and has neuroprotective properties. Withaphysalin D is able to cross the blood-brain barrier[1].

 Names

Name 1-(4-Chlorophenyl)-2-methyl-6-phenyl-4(1H)-pyridinone
Synonym More Synonyms

  Biological Activity

Description Withaphysalin D is a selective antagonist against the N-methyl-D-aspartate receptor (NMDAR) containing GluN2B. Withaphysalin D can be isolated from water lilies and has neuroprotective properties. Withaphysalin D is able to cross the blood-brain barrier[1].
Related Catalog
References

[1]. Kumar G,et al. Exploring neuroprotective potential of Withania somnifera phytochemicals by inhibition of GluN2B-containing NMDA receptors: An in silico study. Med Hypotheses. 2016 Jul;92:35-43.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 451.6±45.0 °C at 760 mmHg
Molecular Formula C18H14ClNO
Molecular Weight 295.763
Flash Point 226.9±28.7 °C
Exact Mass 295.076385
LogP 4.22
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.631

 Synonyms

1-(4-Chlorophenyl)-2-methyl-6-phenyl-4(1H)-pyridinone
4(1H)-Pyridinone, 1-(4-chlorophenyl)-2-methyl-6-phenyl-
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