CHK1-IN-2

Modify Date: 2025-08-25 21:45:43

CHK1-IN-2 Structure
CHK1-IN-2 structure
Common Name CHK1-IN-2
CAS Number 912367-45-4 Molecular Weight 366.48
Density N/A Boiling Point N/A
Molecular Formula C20H22N4OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CHK1-IN-2


CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM.

 Names

Name CHK1-IN-2

 CHK1-IN-2 Biological Activity

Description CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM.
Related Catalog
Target

Chk1:6 nM (IC50)

In Vitro CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM, which is a potential cancer therapeutic that can be utilized for enhancing the efficacy of DNA damaging agents[1].
References

[1]. Yang B, et al. Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) Inhibitors. J Med Chem. 2018 Feb 8;61(3):1061-1073.

 Chemical & Physical Properties

Molecular Formula C20H22N4OS
Molecular Weight 366.48
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