Furowanin A

Modify Date: 2024-02-10 12:01:35

Furowanin A Structure
Furowanin A structure
Common Name Furowanin A
CAS Number 911004-72-3 Molecular Weight 438.47
Density 1.4±0.1 g/cm3 Boiling Point 697.7±55.0 °C at 760 mmHg
Molecular Formula C25H26O7 Melting Point N/A
MSDS N/A Flash Point 240.3±25.0 °C

 Use of Furowanin A


Furowanin A is a flavonoid with anti-neoplastic effects. Furowanin A inhibits STAT3/Mcl-1 axis to suppress proliferation, block cell cycle progression, induce apoptosis and promote autophagy. Furowanin A potently inhibits colorectal cancer (CRC) cells[1].

 Names

Name Furowanin A
Synonym More Synonyms

 Furowanin A Biological Activity

Description Furowanin A is a flavonoid with anti-neoplastic effects. Furowanin A inhibits STAT3/Mcl-1 axis to suppress proliferation, block cell cycle progression, induce apoptosis and promote autophagy. Furowanin A potently inhibits colorectal cancer (CRC) cells[1].
Related Catalog
Target

Mcl-1

STAT3

References

[1]. Ma Z, et al. Furowanin A-induced autophagy alleviates apoptosis and promotes cell cycle arrest via inactivation STAT3/Mcl-1 axis in colorectal cancer. Life Sci. 2019 Feb 1;218:47-57.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 697.7±55.0 °C at 760 mmHg
Molecular Formula C25H26O7
Molecular Weight 438.47
Flash Point 240.3±25.0 °C
Exact Mass 438.167847
PSA 120.36000
LogP 5.34
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.661

 Safety Information

Hazard Codes Xi

 Synonyms

6-(3,4-Dihydroxyphenyl)-4-hydroxy-2-(2-hydroxy-2-propanyl)-9-(3-methyl-2-buten-1-yl)-2,3-dihydro-5H-furo[3,2-g]chromen-5-one
5H-Furo[3,2-g][1]benzopyran-5-one, 6-(3,4-dihydroxyphenyl)-2,3-dihydro-4-hydroxy-2-(1-hydroxy-1-methylethyl)-9-(3-methyl-2-buten-1-yl)-