8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione
Modify Date: 2024-01-03 09:20:54
![8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione Structure](https://www.chemsrc.com/caspic/467/90749-32-9.png)
8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione structure
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Common Name | 8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione | ||
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| CAS Number | 90749-32-9 | Molecular Weight | 500.63500 | |
| Density | 1.21g/cm3 | Boiling Point | 692.5ºC at 760mmHg | |
| Molecular Formula | C29H36N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 372.6ºC | |
Use of 8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dioneLaprafylline is a xanthine compound with inhibitory effects on bronchoconstriction in vivo and antitumor activity.Laprafylline acts as a competitive serotonergic antagonist at low concentrations, and inhibits constriction induced by hist at high difficulties. |
| Name | 8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione |
|---|---|
| Synonym | More Synonyms |
| Description | Laprafylline is a xanthine compound with inhibitory effects on bronchoconstriction in vivo and antitumor activity.Laprafylline acts as a competitive serotonergic antagonist at low concentrations, and inhibits constriction induced by hist at high difficulties. |
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| References | 1. Barupal DK, et al. Generating the Blood Exposome Database Using a Comprehensive Text Mining and Database Fusion Approach. Environ Health Perspect. 2019 Sep;127(9):97008. |
| Density | 1.21g/cm3 |
|---|---|
| Boiling Point | 692.5ºC at 760mmHg |
| Molecular Formula | C29H36N6O2 |
| Molecular Weight | 500.63500 |
| Flash Point | 372.6ºC |
| Exact Mass | 500.29000 |
| PSA | 79.16000 |
| LogP | 2.90480 |
| Index of Refraction | 1.611 |
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~71%
8-[2-(4-benzhyd... CAS#:90749-32-9 |
| Literature: Regnier, Gilbert L.; Guillonneau, Claude G.; Duhault, Jacques L.; Tisserand, Francoise P.; Saint-Romas, Guy; Holstorp, Sophie M. European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 243 - 250 |
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~%
8-[2-(4-benzhyd... CAS#:90749-32-9 |
| Literature: Regnier, Gilbert L.; Guillonneau, Claude G.; Duhault, Jacques L.; Tisserand, Francoise P.; Saint-Romas, Guy; Holstorp, Sophie M. European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 243 - 250 |
|
~73%
8-[2-(4-benzhyd... CAS#:90749-32-9 |
| Literature: Regnier, Gilbert L.; Guillonneau, Claude G.; Duhault, Jacques L.; Tisserand, Francoise P.; Saint-Romas, Guy; Holstorp, Sophie M. European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 243 - 250 |
|
~%
8-[2-(4-benzhyd... CAS#:90749-32-9 |
| Literature: Regnier, Gilbert L.; Guillonneau, Claude G.; Duhault, Jacques L.; Tisserand, Francoise P.; Saint-Romas, Guy; Holstorp, Sophie M. European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 243 - 250 |
| Laprafilina [INN-Spanish] |
| Laprafylline |
| Laprafyllinum [INN-Latin] |
| 8-(2-(4-(Diphenylmethyl)-1-piperazinyl)ethyl)-3-isobutyl-1-methylxanthine |
| 1-methyl-3-isobutyl-8-[2-(4-diphenylmethyl-piperazinyl)ethyl]xanthine |
| S 9795 |
| 1-Methyl-3-isobutyl-8-(2-(4-benzhydrylpiperazino)ethyl)xanthine |