Carebastine

Modify Date: 2025-08-23 10:28:07

Carebastine structure	Common Name	Carebastine
	CAS Number	90729-42-3	Molecular Weight	499.641
	Density	1.2±0.1 g/cm3	Boiling Point	657.9±55.0 °C at 760 mmHg
	Molecular Formula	C₃₂H₃₇NO₄	Melting Point	178-180ºC
	MSDS	N/A	Flash Point	351.7±31.5 °C

Use of Carebastine

Carebastine is the active metabolite of Ebastine. Carebastine is a histamine H1 receptor antagonist. Carebastine inhibits VEGF-induced HUVEC and HPAEC proliferation, migration and angiogenesis in a dose-dependent manner[1]. Carebastine suppresses the expression of macrophage migration inhibitory factor[2].

Name	2-[4-[4-(4-benzhydryloxypiperidin-1-yl)butanoyl]phenyl]-2-methylpropanoic acid
Synonym	More Synonyms

Description	Carebastine is the active metabolite of Ebastine. Carebastine is a histamine H1 receptor antagonist. Carebastine inhibits VEGF-induced HUVEC and HPAEC proliferation, migration and angiogenesis in a dose-dependent manner[1]. Carebastine suppresses the expression of macrophage migration inhibitory factor[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	H1 receptor
References	[1]. De Luisi A, et al. Anti-angiogenic activity of carebastine: a plausible mechanism affecting airway remodelling. Eur Respir J. 2009 Oct;34(4):958-66. [2]. Zhao Y, et al. Carebastine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor. Clin Exp Dermatol. 2008 Nov;33(6):785-7.

Density	1.2±0.1 g/cm3
Boiling Point	657.9±55.0 °C at 760 mmHg
Melting Point	178-180ºC
Molecular Formula	C₃₂H₃₇NO₄
Molecular Weight	499.641
Flash Point	351.7±31.5 °C
Exact Mass	499.272247
PSA	66.84000
LogP	6.09
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.609

p-(4-(4-(Diphenylmethoxy)piperidino)butyryl)-a-methylhydratropic Acid

Carebastinum

carebastine

2-(4-{4-[4-(Diphenylmethoxy)piperidin-1-yl]butanoyl}phenyl)-2-methylpropanoic acid

4-(4-(4-(Diphenylmethoxy)-1-piperidinyl)-1-oxobutyl)-a,a-dimethylbenzeneacetic Acid

Benzeneacetic acid, 4-[4-[4-(diphenylmethoxy)-1-piperidinyl]-1-oxobutyl]-α,α-dimethyl-

Carebastina

C32H37NO4

UNII-75DLN707DO

2-(4-{4-[4-(Diphenylmethoxy)-1-piperidinyl]butanoyl}phenyl)-2-methylpropanoic acid

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Carebastine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-(4-(4-(4-(BENZHYDRYLOXY)PIPERIDIN-1-YL)BUTANOYL)PHENYL)-2-METHYLPROPANOIC ACID
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Get all suppliers and price by the below link:

Carebastine suppliers

Price: ￥550/1 mg

Reference only. check more Carebastine price

Carebastine

Use of Carebastine

Names

Carebastine Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.