Galactofucan

Modify Date: 2024-01-31 19:18:13

Galactofucan Structure
Galactofucan structure
Common Name Galactofucan
CAS Number 9061-39-6 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Galactofucan


Galactofucan (Fucogalactan) is a sulfated polysaccharide. Galactofucan can be extracted from brown seaweed Saccharina longicruris with anticoagulant, anti-tumor, anti-thrombosis, anti-inflammatory and antiviral properties. Galactofucan shows antiviral activities to HSV-1 and HSV-2 with IC50s of 0.76 and 1.34 µg/mL, respectively. Galactofucan can be used for the research of cancer and inflammation[1][2].

 Names

Name fucogalactan

 Galactofucan Biological Activity

Description Galactofucan (Fucogalactan) is a sulfated polysaccharide. Galactofucan can be extracted from brown seaweed Saccharina longicruris with anticoagulant, anti-tumor, anti-thrombosis, anti-inflammatory and antiviral properties. Galactofucan shows antiviral activities to HSV-1 and HSV-2 with IC50s of 0.76 and 1.34 µg/mL, respectively. Galactofucan can be used for the research of cancer and inflammation[1][2].
Related Catalog
Target

HSV-1:0.76 μg/mL (IC50)

HSV-2:1.34 μg/mL (IC50)

In Vitro Galactofucan (0-100 µg/mL; 48 h) shows antiviral activities towards HSV-1 and HSV-2 with IC50s of 0.76 and 1.34 µg/mL, respectively[1].
In Vivo Galactofucan (10-100 mg/kg; i.p. once) (extracted from Agaricus bisporus) shows anti-inflammatory activity[2]. Animal Model: Male Swiss mice with acetic acid intraperitoneal injection[2] Dosage: 10, 30 and 100 mg/kg Administration: Intraperitoneal injection; 10-100 mg/kg once Result: Repressed acetic acid-induced abdominal constriction, inhibited leukocytes migration and peritoneal capillary permeability.
References

[1]. Ponce NMA, et al. Fucoidans from the phaeophyta Scytosiphon lomentaria: Chemical analysis and antiviral activity of the galactofucan component. Carbohydr Res. 2019 May 15;478:18-24.

[2]. Komura DL, et al. Structure of Agaricus spp. fucogalactans and their anti-inflammatory and antinociceptive properties. Bioresour Technol. 2010 Aug;101(15):6192-9.

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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