9061-39-6
9061-39-6 structure
- Name: Galactofucan
- Chemical Name: fucogalactan
- CAS Number: 9061-39-6
- Molecular Formula:
- Molecular Weight:
- Catalog: Signaling Pathways Anti-infection HSV
- Create Date: 2018-11-12 18:17:42
- Modify Date: 2024-01-31 19:18:13
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Galactofucan (Fucogalactan) is a sulfated polysaccharide. Galactofucan can be extracted from brown seaweed Saccharina longicruris with anticoagulant, anti-tumor, anti-thrombosis, anti-inflammatory and antiviral properties. Galactofucan shows antiviral activities to HSV-1 and HSV-2 with IC50s of 0.76 and 1.34 µg/mL, respectively. Galactofucan can be used for the research of cancer and inflammation[1][2].
| Name | fucogalactan |
|---|
| Description | Galactofucan (Fucogalactan) is a sulfated polysaccharide. Galactofucan can be extracted from brown seaweed Saccharina longicruris with anticoagulant, anti-tumor, anti-thrombosis, anti-inflammatory and antiviral properties. Galactofucan shows antiviral activities to HSV-1 and HSV-2 with IC50s of 0.76 and 1.34 µg/mL, respectively. Galactofucan can be used for the research of cancer and inflammation[1][2]. |
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| Related Catalog | |
| Target |
HSV-1:0.76 μg/mL (IC50) HSV-2:1.34 μg/mL (IC50) |
| In Vitro | Galactofucan (0-100 µg/mL; 48 h) shows antiviral activities towards HSV-1 and HSV-2 with IC50s of 0.76 and 1.34 µg/mL, respectively[1]. |
| In Vivo | Galactofucan (10-100 mg/kg; i.p. once) (extracted from Agaricus bisporus) shows anti-inflammatory activity[2]. Animal Model: Male Swiss mice with acetic acid intraperitoneal injection[2] Dosage: 10, 30 and 100 mg/kg Administration: Intraperitoneal injection; 10-100 mg/kg once Result: Repressed acetic acid-induced abdominal constriction, inhibited leukocytes migration and peritoneal capillary permeability. |
| References |
| No Any Chemical & Physical Properties |