CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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FJ5850000
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CHEMICAL NAME :
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Cellulose, carboxymethyl ether, calcium salt
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CAS REGISTRY NUMBER :
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9050-04-8
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LAST UPDATED :
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199701
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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4400 mg/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Behavioral - muscle contraction or spasticity Kidney, Ureter, Bladder - changes in bladder weight
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REFERENCE :
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993
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TYPE OF TEST :
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LC - Lethal concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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>300 mg/m3
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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6800 mg/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Behavioral - muscle contraction or spasticity Kidney, Ureter, Bladder - changes in bladder weight
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REFERENCE :
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993
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TYPE OF TEST :
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LC - Lethal concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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>300 mg/m3
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993
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TYPE OF TEST :
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LC - Lethal concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - guinea pig
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DOSE/DURATION :
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>300 mg/m3
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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52 mg/m3/17W-I
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TOXIC EFFECTS :
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Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
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REFERENCE :
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993
-
TYPE OF TEST :
-
TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - guinea pig
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DOSE/DURATION :
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52 mg/m3/17W-I
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TOXIC EFFECTS :
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Blood - changes in erythrocyte (RBC) count
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REFERENCE :
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(2),29,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2450 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 738 (estimated) No. of Female Employees: 369 (estimated)
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