5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE

Modify Date: 2024-01-12 11:52:20

5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE Structure
5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE structure
Common Name 5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE
CAS Number 90301-60-3 Molecular Weight 272.25
Density 1.496g/cm3 Boiling Point N/A
Molecular Formula C11H16N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE


5-(2-Hydroxyethyl)-2’-deoxy uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-(2-hydroxyethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

 5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE Biological Activity

Description 5-(2-Hydroxyethyl)-2’-deoxy uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.496g/cm3
Molecular Formula C11H16N2O6
Molecular Weight 272.25
Exact Mass 272.10100
PSA 124.78000
Index of Refraction 1.597

 Synthetic Route

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5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE Structure

5-(2-HYDROXYETH...

CAS#:90301-60-3

Literature: European Journal of Organic Chemistry, , # 10 p. 1989 - 1999

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5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE Structure

5-(2-HYDROXYETH...

CAS#:90301-60-3

Literature: Hassan, Mohamed E. Recueil des Travaux Chimiques des Pays-Bas, 1986 , vol. 105, # 1 p. 30 - 32

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5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE Structure

5-(2-HYDROXYETH...

CAS#:90301-60-3

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 105, # 1 p. 30 - 32

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5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE Structure

5-(2-HYDROXYETH...

CAS#:90301-60-3

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 105, # 1 p. 30 - 32