ML-261
Modify Date: 2024-02-23 12:20:53
ML-261 structure
|
Common Name | ML-261 | ||
|---|---|---|---|---|
| CAS Number | 902523-58-4 | Molecular Weight | 406.926 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 625.4±55.0 °C at 760 mmHg | |
| Molecular Formula | C20H23ClN2O3S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 332.0±31.5 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of ML-261ML261 is a hepatic lipid droplets formation inhibitor with an IC50 value of 69.7 nM. ML261 can be used for the research of non-alcoholic fatty liver disease (NAFLD) and inflammation[1]. |
| Name | 2-Chloro-N-[2-(3,4-diethoxyphenyl)ethyl]-4-methyl-4H-thieno[3,2-b ]pyrrole-5-carboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | ML261 is a hepatic lipid droplets formation inhibitor with an IC50 value of 69.7 nM. ML261 can be used for the research of non-alcoholic fatty liver disease (NAFLD) and inflammation[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 69.7 nM (hepatic lipid droplets formation)[1] |
| In Vitro | ML261 (1 nM-10 μM; 24 h) affects hepatic lipid droplets formation in murine AML-12 cells[1]. Cell Viability Assay[1] Cell Line: AML-12 cells Concentration: 1 nM-10 μM Incubation Time: 24 hours Result: Inhibited hepatic lipid droplets formation with an IC50 value of 69.7 nM. |
| References |
[1]. Zou J, et al. Potent inhibitors of lipid droplet formation. 2014. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 625.4±55.0 °C at 760 mmHg |
| Molecular Formula | C20H23ClN2O3S |
| Molecular Weight | 406.926 |
| Flash Point | 332.0±31.5 °C |
| Exact Mass | 406.111786 |
| PSA | 84.22000 |
| LogP | 5.45 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.610 |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| RIDADR | UN 2811 6.1 / PGIII |
| 2-Chloro-N-[2-(3,4-diethoxyphenyl)ethyl]-4-methyl-4H-thieno[3,2-b]pyrrole-5-carboxamide |
| 4H-Thieno[3,2-b]pyrrole-5-carboxamide, 2-chloro-N-[2-(3,4-diethoxyphenyl)ethyl]-4-methyl- |