Neuraminidase

Modify Date: 2024-01-02 08:05:58

Neuraminidase Structure
Neuraminidase structure
Common Name Neuraminidase
CAS Number 9001-67-6 Molecular Weight 226.232
Density 1.4±0.1 g/cm3 Boiling Point 656.2±55.0 °C at 760 mmHg
Molecular Formula C9H14N4O3 Melting Point N/A
MSDS Chinese USA Flash Point 350.7±31.5 °C

 Use of Neuraminidase


Neuraminidase (Exo-α-sialidase) is an exosialidase, is often used in biochemical studies. Neuraminidase cleaves α-ketosidic linkage between the sialic (N-acetylneuraminic) acid and an adjacent sugar residue. Neuraminidase, derived from mucosal pathogens, is a virulence factor that modifies the host's response to infection[1].

 Names

Name carnosine
Synonym More Synonyms

 Neuraminidase Biological Activity

Description Neuraminidase (Exo-α-sialidase) is an exosialidase, is often used in biochemical studies. Neuraminidase cleaves α-ketosidic linkage between the sialic (N-acetylneuraminic) acid and an adjacent sugar residue. Neuraminidase, derived from mucosal pathogens, is a virulence factor that modifies the host's response to infection[1].
Related Catalog
References

[1]. Shtyrya YA, et al. Influenza virus neuraminidase: structure and function. Acta Naturae. 2009 Jul;1(2):26-32.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 656.2±55.0 °C at 760 mmHg
Molecular Formula C9H14N4O3
Molecular Weight 226.232
Flash Point 350.7±31.5 °C
Exact Mass 226.106583
LogP -2.17
Appearance of Characters lyophilized powder | white
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.591
Storage condition 2-8°C
Water Solubility Soluble in water or 10mM phosphate buffer, pH 6.0

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS QQ3450000

 Articles86

More Articles
Neuraminidase inhibitors for influenza: a review and public health perspective in the aftermath of the 2009 pandemic.

Influenza Other Respi. Viruses 7 Suppl 1 , 14-24, (2013)

The objectives of this study were to: (1) reflect on key stages in the discovery, development and pre-pandemic use of neuraminidase inhibitors (NAIs), (2) summarise the evidence of NAI effectiveness f...

Genetic ancestor of external antigens of pandemic influenza A/H1N1 virus.

Interdiscip. Sci. 4(4) , 282-90, (2012)

The aim of the present investigation was to discover the genetic relationships of 2009 pandemic novel influenza A/H1N1 virus (NIV) external antigens Hemagglutinin (HA) and Neuraminidase (NA) with othe...

Nucleic acid-based detection of influenza A virus subtypes H7 and N9 with a special emphasis on the avian H7N9 virus.

Euro Surveill. 19(10) , (2014)

In 2013, a novel influenza A virus of subtype H7N9 was transmitted from avian sources to humans in China, causing severe illness and substantial mortality. Rapid and sensitive diagnostic approaches ar...

 Synonyms

2-[(3-Aminopropanoyl)amino]-3-(1H-imidazol-4-yl)propanoic acid
Histidine, β-alanyl-
b-Alanylhistidine
β-Alanylhistidine
carnosine
EINECS 232-624-6
MFCD00131711
N-(3-Aminopropanoyl)histidine