Neuraminidase-IN-2

Modify Date: 2024-04-07 15:47:32

Neuraminidase-IN-2 Structure
Neuraminidase-IN-2 structure
Common Name Neuraminidase-IN-2
CAS Number 2599015-44-6 Molecular Weight 510.62
Density N/A Boiling Point N/A
Molecular Formula C29H38N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Neuraminidase-IN-2


Neuraminidase-IN-2 is an anti-influenza compounds with IC50 values of 0.28, 0.27, 11.50, 0.089 and 23.44 µM for H1N1, 09H1N1, H3N2, H5N1 and H5N2, respectively. Neuraminidase-IN-2 has antiviral activity and low cytotoxicity[1].

 Names

Name Neuraminidase-IN-2

 Neuraminidase-IN-2 Biological Activity

Description Neuraminidase-IN-2 is an anti-influenza compounds with IC50 values of 0.28, 0.27, 11.50, 0.089 and 23.44 µM for H1N1, 09H1N1, H3N2, H5N1 and H5N2, respectively. Neuraminidase-IN-2 has antiviral activity and low cytotoxicity[1].
Related Catalog
In Vivo Neuraminidase-IN-2 (Compound 5c) (1 g/kg;灌胃;单剂量) 对小鼠毒性较低,不显著增加小鼠的体重[1]。
References

[1]. Jia R, et al. Discovery of highly potent and selective influenza virus neuraminidase inhibitors targeting 150-cavity. Eur J Med Chem. 2021 Feb 15;212:113097.  

 Chemical & Physical Properties

Molecular Formula C29H38N2O6
Molecular Weight 510.62