S3QEL 2

Modify Date: 2025-08-25 18:44:48

S3QEL 2 Structure
S3QEL 2 structure
Common Name S3QEL 2
CAS Number 890888-12-7 Molecular Weight 323.44
Density N/A Boiling Point N/A
Molecular Formula C19H25N5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of S3QEL 2


S3QEL-2, a suppressor of superoxide production from mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production (IC50=1.7 μM). S3QEL-2 does not affect oxidative phosphorylation, and normal electron flux. S3QEL-2 inhibits HIF-1α accumulation[1].

 Names

Name S3QEL-2

 S3QEL 2 Biological Activity

Description S3QEL-2, a suppressor of superoxide production from mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production (IC50=1.7 μM). S3QEL-2 does not affect oxidative phosphorylation, and normal electron flux. S3QEL-2 inhibits HIF-1α accumulation[1].
Related Catalog
In Vitro S3QELs-2 protects against ROS-induced, JNK-mediated cell stress in pancreatic β-cells and S3QEL-2 strongly mitigates the oxidative stress-induced apoptosis that limits the yield of functional β-cells from intact islets[1].
References

[1]. Orr AL, et al. Suppressors of superoxide production from mitochondrial complex III. Nat Chem Biol. 2015;11(11):834-836.

 Chemical & Physical Properties

Molecular Formula C19H25N5
Molecular Weight 323.44
InChIKey MGIAJZSCNPODRR-UHFFFAOYSA-N
SMILES CCCN(CCC)c1ncnc2c1cnn2-c1ccc(C)c(C)c1
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