890888-12-7
890888-12-7 structure
- Name: S3QEL 2
- Chemical Name: S3QEL-2
- CAS Number: 890888-12-7
- Molecular Formula: C19H25N5
- Molecular Weight: 323.44
- Catalog: Research Areas Metabolic Disease
- Create Date: 2020-11-26 12:56:36
- Modify Date: 2025-08-25 18:44:48
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S3QEL-2, a suppressor of superoxide production from mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production (IC50=1.7 μM). S3QEL-2 does not affect oxidative phosphorylation, and normal electron flux. S3QEL-2 inhibits HIF-1α accumulation[1].
| Name | S3QEL-2 |
|---|
| Description | S3QEL-2, a suppressor of superoxide production from mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production (IC50=1.7 μM). S3QEL-2 does not affect oxidative phosphorylation, and normal electron flux. S3QEL-2 inhibits HIF-1α accumulation[1]. |
|---|---|
| Related Catalog | |
| In Vitro | S3QELs-2 protects against ROS-induced, JNK-mediated cell stress in pancreatic β-cells and S3QEL-2 strongly mitigates the oxidative stress-induced apoptosis that limits the yield of functional β-cells from intact islets[1]. |
| References |
| Molecular Formula | C19H25N5 |
|---|---|
| Molecular Weight | 323.44 |