Metorphamide (free acid)
Metorphamide (free acid) structure
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Common Name | Metorphamide (free acid) | ||
|---|---|---|---|---|
| CAS Number | 88866-92-6 | Molecular Weight | 985.16400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C44H68N14O10S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Name | adrenorphin |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C44H68N14O10S |
|---|---|
| Molecular Weight | 985.16400 |
| Exact Mass | 984.49600 |
| PSA | 436.35000 |
| LogP | 2.99980 |
| InChIKey | ZBRXWGQCHSFAHM-MWSMAVIUSA-N |
| SMILES | CSCCC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc1ccc(O)cc1)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(=O)O)C(C)C |
| Storage condition | -20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3.0 |
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MDR1 P-glycoprotein transports endogenous opioid peptides.
Peptides 22 , 2015-2020, (2001) MDR1 P-glycoprotein is generally regarded as an efflux pump for amphipathic toxic compounds. The question remains, however, whether certain endogenous compounds are also substrates for this transporte... |
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Metorphamide, a novel endogenous adrenal opioid peptide, inhibits nicotine-induced secretion from bovine adrenal chromaffin cells.
Brain Res. 363 , 10-17, (1986) Opioid peptides are found in high concentrations in the adrenal medulla. Recently, a novel opioid octapeptide, metorphamide, possessing an amidated C-terminal, was characterized and also found to be p... |
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Opioid inhibition of nicotine-induced 45Ca2(+)-uptake into cultured bovine adrenal medullary cells.
Biochem. Pharmacol. 41 , 715-722, (1991) The ability of a number of opioid agonists and antagonists to affect nicotine-induced 45Ca2(+)-uptake into cultured bovine adrenal medullary cells has been investigated. High (10 microM) concentration... |
| TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL |
| METORPHINAMIDE |
| Adrenorphin,Free Acid |
| METORPHAMIDE |
| H-TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-OH |
| Metorphamide (free acid) |