WQ3810

Modify Date: 2024-09-14 21:09:11

Use of WQ3810

WQ3810 is an orally active fluoroquinolone, with potent antibacterial activities.

Name	1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-8-methyl-4-oxo-7-[3-(propan-2-ylamino)azetidin-1-yl]quinoline-3-carboxylic acid
Synonym	More Synonyms

Description	WQ3810 is an orally active fluoroquinolone, with potent antibacterial activities.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection
In Vitro	WQ-3810 shows potent activity against A. baumannii, including MDR isolates, with MIC90 of 1 mg/L, more than eight-fold higher than that of ciprofloxacin (64 mg/L) and levofloxacin (8 mg/L). WQ-3810 also exhibits inhibitory effects on E. coli and S. pneumoniae, including FQR isolates, with MIC90 of 4 mg/L and 0.06 mg/L, respectively. WQ-3810 is the most potent among the fluoroquinolones tested against meticillin-resistant Staphylococcus aureus (MRSA) and Neisseria gonorrhoeae, including FQR isolates[1].
References	[1]. Kazamori D, et al. In vitro activity of WQ-3810, a novel fluoroquinolone, against multidrug-resistant and fluoroquinolone-resistant pathogens. Int J Antimicrob Agents. 2014 Nov;44(5):443-9.

Molecular Formula	C₂₂H₂₂F₃N₅O₃
Molecular Weight	461.43700
Exact Mass	461.16700
PSA	114.21000
LogP	2.96440
InChIKey	MJMVUQNNSOBCGF-UHFFFAOYSA-N
SMILES	Cc1c(N2CC(NC(C)C)C2)c(F)cc2c(=O)c(C(=O)O)cn(-c3nc(N)c(F)cc3F)c12

KPI-10 free base

WQ-3810

UNII-RTQ8P0159M

WQ3810

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Price: $4752/1mg

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