Mad1 (6-21)
Modify Date: 2025-08-25 17:30:47
Mad1 (6-21) structure
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Common Name | Mad1 (6-21) | ||
|---|---|---|---|---|
| CAS Number | 880150-82-3 | Molecular Weight | 1966.29 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C84H140N24O26S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Mad1 (6-21)Mad1 (6-21) is the 6-21 fragment of Mad1 protein. Mad1 (6-21) binds to mammalian Sin3A PAH2 with a Kd of ~29 nM[1]. |
| Name | Mad1 (6-21) |
|---|
| Description | Mad1 (6-21) is the 6-21 fragment of Mad1 protein. Mad1 (6-21) binds to mammalian Sin3A PAH2 with a Kd of ~29 nM[1]. |
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| Related Catalog | |
| In Vitro | The PAH2 domain of mSin3A adopts a left-handed, up-and-down, four-helix bundle structure with residues in all four helices as well as in the turn regions defining a compact structural domain with an extensive hydrophobic core. Helices α1 and α2 form a deep hydrophobic pocket, which constitutes the primary interaction surface for the Mad1 (6-21) peptide. The Mad1 (6-21) forms an amphipathic α helix in the complex and interacts with PAH2 mainly through the apolar surface of the helix[1]. |
| References |
| Molecular Formula | C84H140N24O26S2 |
|---|---|
| Molecular Weight | 1966.29 |
| InChIKey | ZBAJHFNGYUVVPZ-ZJZZMTSFSA-N |
| SMILES | CCC(C)C(NC(=O)C(CC(N)=O)NC(=O)C(CCSC)NC(=O)C(N)CCCNC(=N)N)C(=O)NC(CCC(N)=O)C(=O)NC(CCSC)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)O |