880150-82-3
880150-82-3 structure
- Name: Mad1 (6-21)
- Chemical Name: Mad1 (6-21)
- CAS Number: 880150-82-3
- Molecular Formula: C84H140N24O26S2
- Molecular Weight: 1966.29
- Catalog: Research Areas Neurological Disease
- Create Date: 2021-09-05 17:26:46
- Modify Date: 2025-08-25 17:30:47
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Mad1 (6-21) is the 6-21 fragment of Mad1 protein. Mad1 (6-21) binds to mammalian Sin3A PAH2 with a Kd of ~29 nM[1].
| Name | Mad1 (6-21) |
|---|
| Description | Mad1 (6-21) is the 6-21 fragment of Mad1 protein. Mad1 (6-21) binds to mammalian Sin3A PAH2 with a Kd of ~29 nM[1]. |
|---|---|
| Related Catalog | |
| In Vitro | The PAH2 domain of mSin3A adopts a left-handed, up-and-down, four-helix bundle structure with residues in all four helices as well as in the turn regions defining a compact structural domain with an extensive hydrophobic core. Helices α1 and α2 form a deep hydrophobic pocket, which constitutes the primary interaction surface for the Mad1 (6-21) peptide. The Mad1 (6-21) forms an amphipathic α helix in the complex and interacts with PAH2 mainly through the apolar surface of the helix[1]. |
| References |
| Molecular Formula | C84H140N24O26S2 |
|---|---|
| Molecular Weight | 1966.29 |