JNJ 303
Modify Date: 2025-08-27 02:15:08
JNJ 303 structure
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Common Name | JNJ 303 | ||
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| CAS Number | 878489-28-2 | Molecular Weight | 440.98400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H29ClN2O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JNJ 303JNJ 303 is a potent IKs blocker with an IC50 value of 64 nM. JNJ 303 does not have any effects on other cardiac channels at concentrations of 3.3 μM for INa, Ica, Ito, and IKr. JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP)[1]. |
| Name | 2-(4-chlorophenoxy)-N-[(1R,3S)-5-(methanesulfonamido)-2-adamantyl]-2-methylpropanamide |
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| Synonym | More Synonyms |
| Description | JNJ 303 is a potent IKs blocker with an IC50 value of 64 nM. JNJ 303 does not have any effects on other cardiac channels at concentrations of 3.3 μM for INa, Ica, Ito, and IKr. JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP)[1]. |
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| Related Catalog | |
| Target |
IC50: 64 nM (IKs)[1] |
| References |
| Molecular Formula | C21H29ClN2O4S |
|---|---|
| Molecular Weight | 440.98400 |
| Exact Mass | 440.15400 |
| PSA | 96.37000 |
| LogP | 5.42210 |
| jnj 303 |