AZD-5069
Modify Date: 2024-01-02 11:44:02
AZD-5069 structure
|
Common Name | AZD-5069 | ||
|---|---|---|---|---|
| CAS Number | 878385-84-3 | Molecular Weight | 476.518 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 680.5±65.0 °C at 760 mmHg | |
| Molecular Formula | C18H22F2N4O5S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 365.4±34.3 °C | |
Use of AZD-5069AZD-5069 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment. |
| Name | azd-5069 |
|---|---|
| Synonym | More Synonyms |
| Description | AZD-5069 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment. |
|---|---|
| Related Catalog | |
| Target |
125I-IL-8-CXCR2 |
| In Vitro | AZD-5069 (Compound 2) acts as CXCR2 antagonist by inhibition of [125I]-IL-8 binding to human CXCR2 receptors and as inhibitor of GROα-induced Ca2+ flux in human neutrophils loaded with fluo-3 dye[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 680.5±65.0 °C at 760 mmHg |
| Molecular Formula | C18H22F2N4O5S2 |
| Molecular Weight | 476.518 |
| Flash Point | 365.4±34.3 °C |
| Exact Mass | 476.099976 |
| LogP | 2.43 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.651 |
| Storage condition | 2-8℃ |
| 1-Azetidinesulfonamide, N-[2-[[(2,3-difluorophenyl)methyl]thio]-6-[(1R,2S)-2,3-dihydroxy-1-methylpropoxy]-4-pyrimidinyl]- |
| N-(2-[(2,3-Difluorobenzyl)sulfanyl]-6-{[(2R,3S)-3,4-dihydroxy-2-butanyl]oxy}-4-pyrimidinyl)-1-azetidinesulfonamide |