871656-65-4
871656-65-4 structure
- Name: AZD-1092
- Chemical Name: AZD-1092
- CAS Number: 871656-65-4
- Molecular Formula: C24H26N4O5
- Molecular Weight: 450.495
- Create Date: 2020-01-12 09:25:49
- Modify Date: 2024-04-12 23:21:49
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AZD-1092 (GKA-80) is a potent Glucokinase (GK) activator with EC50 of 30 nM; exhibits dose dependent reduction of glucose excursion in oral glucose tolerance tests in high fat fed female Zucker rats; shows potential for treatment of type 2 diabetes.
| Name | AZD-1092 |
|---|
| Description | AZD-1092 (GKA-80) is a potent Glucokinase (GK) activator with EC50 of 30 nM; exhibits dose dependent reduction of glucose excursion in oral glucose tolerance tests in high fat fed female Zucker rats; shows potential for treatment of type 2 diabetes. |
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| References | References 1. Coope GJ, et al. Br J Pharmacol. 2006 Oct;149(3):328-35. 2. Michael J. Waring, et al. Med. Chem. Commun., 2011, 2, 775-779 View Related Products by Target Glucokinase |
| Molecular Formula | C24H26N4O5 |
|---|---|
| Molecular Weight | 450.495 |